?
  Home

 
 
-
-

Recombinant Human IGFBP-2

Description :

IGFBPs controls the distribution, function and activity of IGFs in various cell tissues and body fluids. Currently there are seven named IGF-BPs that form high affinity complexes with both IGF-I and IGF-II. IGFBP-2 is a cysteine-rich secreted protein produced by bone cells, and is most abundant in the brain. IGFBP-2 has been shown to inhibit IGF-II action in human breast and ovarian carcinoma cells. Recombinant human IGFBP-2 is a 31.5 kDa protein consisting of 289 amino acid residues including the IGFBP domain and thyroglobulin type-I domain.

Catalog #:

003-IGFBP2

Source:

High-5 (BTI-Tn-5B1-4) Insect Cells

Stability:

The lyophilized protein is stable for a few weeks at room temperature, but best stored at -200C. Reconstituted h-IGFBP-2 should be stored in working aliquots at -200C.

Purity:

Greater than 98% by SDS-PAGE and HPLC analyses.

Endotoxin Level:

Endotoxin level is less than 0.1 ng per μg (1EU/μg).

Biological Activity:

Determined by its ability to inhibit IGF-I or IGF-II induced proliferation of FDC-P1 cells.

AA Sequence:

EVLFRCPPCT PERLAACGPP PVAPPAAVAA VAGGARMPCA ELVREPGCGC CSVCARLEGE ACQVYTPRCG QGLRCYPHPG SELPLQALVM GEGTCEKRRD AEYGASPEQV ADNGDDHSEG GLVENHVDST MNMLGGGGSA GRKPLKSGMK ELAVFREKVT EQHRQMGKGG KHHLGLEEPK KLRPPPARTP CQQELDQVLE RISTMRLPDE RGPLEHLYSL HIPNCDKHGL YNLKQCKMSL NGQRGECWCV NPNTGKLIQG APTIRGDPEC HLFYNEQQEA RGVHTQRMQ

PubMed  Link :

IGFBP-2

Usage:

For research Purposes Only - Made using a cell BTI-Tn-5B1-4 under license from the Boyce Thompson Institute for Plant Research, Inc. Not for use in diagnostic or therapeutic procedures.

Country of Origin:

USA



Request a Quote or more Information.


Contact Us for more information about this product or SBH Sciences.

> Return to the SBH Products Page


-
-
- - -


Discovery Research Products & Services
(508) 650-6218 | Info@SBHsciences.com
The World's Leading Provider of Cytokine Cell-Based Assays