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Simple Western Services

SBH Sciences and SBH Diagnostics offer an automated Simple Western Blot CRO service on our upgraded Technologies - "PeggySue" and "Wes".  

Peggy Sue Wes
PeggySue Wes

 


We are seeking projects to help you utilize our automated capillary Western Blot service, either Charge (IEF) or Molecular Weight analysis, in our CLIA certified GLP labs. We have worked with many leading pharma companies and universities over the past 2 years providing quality service in over 20,000 assays.

The use of our newest automated Western Blot technologies, PeggySue and Wes, has shown to increase sensitivities greater than 10 fold over standard westerns, as well as to provide valuable capabilities:

  1. Quantitative over 2 logs of protein concentration
  2. Reproducible protein analysis with CVs under 10%
  3. High throughput and cost effective
  4. Multiplexed and normalized to standard proteins

The following is a partial list of Simple Western projects performed by SBH:

  1. Drug responses affecting protein concentrations
  2. Analysis of Lot to Lot production and purification of Biotherapeutics (IL-12, mAbs)
  3. Biomarker Identification: analysis of specific Proteins and Protein Phosphorylations (companion biomarkers) that change over time upon treatment
  4. Drug response in tumor Fine Needle Aspirates
  5. Analysis of cell lines and antibodies
  6. Analysis of cellular preparations with Drug treatment

We welcome the opportunity to connect with you and your colleagues to evaluate your projects, at no charge, to determine how we can best assist you.

See more technical information about our Simple Western Applications and capabilities.

Simple Plex Services

SBH Sciences offers Simple Plex CRO service on our Ella. Ella

The Simple  platform is a transformative immunoassay technology which integrates an innovatively designed microfluidic cartridge with a state-of-the-art analyzer to deliver the most efficient benchtop immunoassay system along with reliable results. It brings a level of automation to the traditional ELISA by providing "sample-to-answer" test results in a sealed disposable cartridge within 1 hour while removing operator related biases. In addition, because of its unique multi-analyte capability with none of the drawbacks of traditional multiplex platforms, this platform has broad applicability in both research and clinical markets. Simple Plex assays have the same specificity of single-plex ELISA, only with sub-picogram detection limits, a 4-5 log dynamic range and single-digit CVs. Ella only uses 25 µL of sample! Ella's also a big believer in standard curves, but doesn't think they need to be run every time. That's why she uses her built-in factory curves instead. The end result? You'll get data quality you've never seen before with ELISA!

More than 120 validated analyses can be tested at SBH Sciences. Full list is available at: 
http://www.proteinsimple.com/simple_plex_assays.html

We at SBH Sciences are offering both immunoassy platforms, the Luminex and the Simple Plex Platforms to meet customers' complete workflow in their research and clinical protein applications. 

Please contact us so we can discuss your specific needs, and ways in which SBH Sciences might be able to work with you. We will be happy to assist you.

Our expertise is your competitive edge!


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Discovery Research Products & Services
(508) 650-6218 | Info@SBHsciences.com
The World's Leading Provider of Cytokine Cell-Based Assays