Description : |
Interleukin-12 is a disulfide-linked heterodimeric protein (p70),
composed of two subunits, p35 and p40, which are encoded by two different genes.
Accumulating data indicate that p40 secretion precedes that of IL-12 expression.
In addition, to its ability to covalently bind to p35 to form IL-12, p40 can bind to
p19 to form IL-23. Recombinant murine IL-12 p40 is a 40 kDa protein containing 313 amino acid residues.
|
Catalog #: |
001-MIL12P40 |
Source : |
CHO cells (Chinese Hamster Ovarian Cells) |
Formulation : |
Sterile filtered and then the protein was lyophilized in 1 x PBS pH 6.8. |
Stability : |
The lyophilized protein is stable for a few weeks at room temperature, but best stored at -200C .
Reconstituted IL-12 p40 should be stored in working aliquots at -200C .
|
Purity : |
Greater than 97% by SDS-PAGE and HPLC analysis. Endotoxin level is less than 0.1 ng per μg (1EU/μg). |
Reconstitution : |
We recommend a quick spin followed by reconstitution in 200 ul of sterile water for injection for 0.5 mg/ml concentration .
This solution can then be diluted into other aqueous buffers and stored at 40C for 3 months or below -100C for future use.
|
Biological Activity : |
Murine IL-12 p40 has no IL-12 (p70) antagonist activity.
|
PubMed Link : |
IL-12 p40 Murine |
Usage: |
For research only. Not for use in diagnostic or therapeutic procedures. |
Country of Origin : |
USA |
