About SBH

Our Mission

Our mission is to offer superior products and services and provide exemplary customer service, with open communication and on-time delivery. We support entrepreneurial scientists and startups, diagnostic, pharmaceutical, and biotechnology companies with unparalleled experience and expertise that significantly shortens timelines and reduces costs.

History of SBH Sciences

sbh_years300-1 SBH Sciences, Inc. was founded in 1997 with the sole purpose of producing mammalian-derived recombinant cytokines. Since 1999, we have expanded our activities to include cell-based bioassays, in-vitro anti-cancer and anti-inflammatory lead compound screening, and the development of ELISA kits and biomarker analyses. We have continued our growth through partnerships with several companies. Our product line now includes monoclonal antibodies and specific glycosyltransferase enzymes. We have increased our biomarker analysis capabilities by offering AlphaScreen/AlphaLISA, analytical HPLC, ELISA, ELLA, flow cytometry, HTRF®, Luminex, MSD, Peggy Sue / WES / Jess, SMCxPRO, IsoLight and real-time PCR platforms.

What We Do and Our Accomplishments

SBH Sciences, Inc. is a preclinical CRO (Contract Research Organization) offering extensive products and services including:

  • Analysis of over 150 biomarkers with expanded multiplex analysis capabilities
  • Multiple cell-based disease models, including 370 human cancer cell lines
  • Hundreds of cell-based assays for cytokine and chemokine activity
  • Commercial production of recombinant cytokines, recombinant glycosyltransferase enzymes, monoclonal antibodies, and ELISA kits

SBH Sciences is the world leader in cell-based assays to measure biological activity of cytokines and growth factors. Our proprietary processes have led to the development and commercialization of 30 highly purified recombinant cytokines and 33 monoclonal antibodies, and we are currently the only commercial source for human GDF-15/MIC-1. SBH Sciences has provided services to over 300 biotechnology companies across the globe during our 25 years of business.

How SBH Sciences Can Help You

SBH Sciences streamlines the process of discovery and biopharmaceutical development by efficiently and effectively using our resources and knowledge. The multitude of products and services we offer can be customized to meet your company's specific needs. We can provide you with time- and cost-saving options to give your company a competitive edge in the industry.

SBH LeadershipDr. Raphael Nir

Dr. Raphael Nir has served as President and Chief Scientific Officer of SBH Sciences since co-founding the company in 1997. He started SBH Sciences to fulfill his dream of becoming a key player in the biotech arena, and to help companies develop drugs. Under his management, SBH Sciences has become a leading supplier of recombinant cytokines and a preferred discovery research service provider.

Raphael is an ambitious entrepreneur and has co-founded seven additional biotech and diagnostics companies: Karyopharm Therapeutics, SBH Diagnostics, Woodland Biosciences, Galectin Sciences, Alma Bio Therapeutics, Vuja De Sciences and NeuroDex. To fulfill his vision and help startup companies, he co-founded two additional companies; Sky Ventures and ABI-LAB; a 7-year old bioincubator located in Natick, MA, currently housing 45 biotechnology companies.

Prior to SBH Sciences formation, Raphael earned his Ph.D. in biotechnology as well as a M.S. in biochemistry, and a B.S. in chemistry from Tel-Aviv University. His postdoctoral research was at Schering Plough Research Institute where he later became a Senior Scientist/Associate Principal Scientist and developed innovative cell culture processes and solutions related to biological production. Additionally, he earned a M.S. in engineering management from New Jersey Institute of Technology (1997).

Ventures at SBH

SBH Sciences is excited to expand its offerings and assist entrepreneurs with our new division, Ventures at SBH.

Ventures at SBH aims to incubate breakthrough scientific ideas and to support entrepreneurs in the early stages of research and development. SBH offers extensive lab space, equipment, scientific expertise, business development, grant submission assistance, networking opportunities, and early / seed-stage investments.

Expanding Services

SBH Sciences established two strategic partnerships expanding our services to cover the drug-discovery spectrum from in-vitro lead optimization through innovative animal modeling and companion diagnostics. In addition, SBH has partnered with ABI-LAB, a Boston-based Accelerator and Bio-Incubator, to offer 60 affordable lab spaces as well as innovative pre-clinical services. Find more details in our company presentation.


SBH Diagnostics: An innovative GLP and CLIA Certified CRO (Contract Research Organization), dedicated to providing accurate and reproducible Biomarker Laboratory services supporting preclinical and clinical studies.


ABI-LAB: Boston-based Accelerator and Bio-Incubator