---
title: Human BMP-2 Recombinant Protein
description: Activin-A is a TGF-beta family member involved in the regulation of cellular proliferation and differentiation, and promotion of neuronal survival.
image: https://sbhsciences.com/hubfs/Screenshot%202026-01-20%20at%202.06.00%20PM.png
---

<https://sbhsciences.com/blog/human-bmp-2-recombinant-protein#body>

[![SBH Sciences](https://sbhsciences.com/hs-fs/hubfs/Imported%20sitepage%20images/sbhlogo.png?width=155&height=74&name=sbhlogo.png "SBH Sciences")](https://sbhsciences.com/)

- Open submenu for ABOUT US 
  
    - [ABOUT SBH](https://sbhsciences.com/about-sbh)
    - [LEADERSHIP](https://sbhsciences.com/sbh-leadership)
    - [CONTACT](https://sbhsciences.com/contact)
    - [CAREERS](https://sbhsciences.com/careers)
- [SBH BIOVENTURE](https://sbhsciences.com/sbh-bioventure)
- [SOLUTIONS](https://sbhsciences.com/services)
  
   Show submenu for SOLUTIONS 
  
    - [CELL BASED ASSAYS](https://sbhsciences.com/cell-based-assay-services)
    - Open submenu for PRODUCT SERVICES 
      
          - [PROTEINS](https://sbhsciences.com/protein-production-services)
          - [MOLECULAR BIOLOGY](https://sbhsciences.com/molecular-biology-services)
          - [CELL CULTURE](https://sbhsciences.com/cell-culture-services)
          - [ORGANOIDS](https://sbhsciences.com/blog/organoids-mini-organs-grown-for-research-and-drug-development)
          - [EXOSOMES](https://sbhsciences.com/exosome-services)
    - [BIOMARKER TESTING](https://sbhsciences.com/biomarker-testing)
    - Open submenu for DRUG DISCOVERY 
      
          - [ADCC](https://sbhsciences.com/antibody-development-1)
          - [ELISA](https://sbhsciences.com/elisa-assays)
          - [BIOANALYTICAL](https://sbhsciences.com/bioanalytical-discovery-services)
          - [BIOSIMILARS](https://sbhsciences.com/biosimilars)
          - [CELL & GENE THERAPY](https://sbhsciences.com/cgt)
          - [SMALL MOLECULE](https://sbhsciences.com/small-molecule)
    - [FTE MODEL](https://sbhsciences.com/fte-model)
    - [CONSULTING](https://sbhsciences.com/mentoring)
- Open submenu for INDICATIONS 
  
    - [NEUROLOGY](https://sbhsciences.com/neurology)
    - [METABOLIC](https://sbhsciences.com/metabolic)
    - [ONCOLOGY](https://sbhsciences.com/oncology)
    - [KIDNEY](https://sbhsciences.com/kidney)
    - [MUSCLE](https://sbhsciences.com/muscle)
- Open submenu for PRODUCTS 
  
    - [CYTOKINES](https://sbhsciences.com/cytokines)
    - [MONOCLONAL ANTIBODIES](https://sbhsciences.com/monoclonal-antibodies)
    - [GLYCOBIOLOGY](https://sbhsciences.com/glycobiology)
- Open submenu for INSIGHTS 
  
    - [NEWS AND BLOG](https://sbhsciences.com/sbh-blog-and-news)
    - [REFERENCES AND PUBLICATIONS](https://sbhsciences.com/references)
    - [STRATEGIC PARTNERSHIPS](https://sbhsciences.com/partnerships)

- Open submenu for ABOUT US 
  
    - [ABOUT SBH](https://sbhsciences.com/about-sbh)
    - [LEADERSHIP](https://sbhsciences.com/sbh-leadership)
    - [CONTACT](https://sbhsciences.com/contact)
    - [CAREERS](https://sbhsciences.com/careers)
- [SBH BIOVENTURE](https://sbhsciences.com/sbh-bioventure)
- [SOLUTIONS](https://sbhsciences.com/services)
  
   Show submenu for SOLUTIONS 
  
    - [CELL BASED ASSAYS](https://sbhsciences.com/cell-based-assay-services)
    - Open submenu for PRODUCT SERVICES 
      
          - [PROTEINS](https://sbhsciences.com/protein-production-services)
          - [MOLECULAR BIOLOGY](https://sbhsciences.com/molecular-biology-services)
          - [CELL CULTURE](https://sbhsciences.com/cell-culture-services)
          - [ORGANOIDS](https://sbhsciences.com/blog/organoids-mini-organs-grown-for-research-and-drug-development)
          - [EXOSOMES](https://sbhsciences.com/exosome-services)
    - [BIOMARKER TESTING](https://sbhsciences.com/biomarker-testing)
    - Open submenu for DRUG DISCOVERY 
      
          - [ADCC](https://sbhsciences.com/antibody-development-1)
          - [ELISA](https://sbhsciences.com/elisa-assays)
          - [BIOANALYTICAL](https://sbhsciences.com/bioanalytical-discovery-services)
          - [BIOSIMILARS](https://sbhsciences.com/biosimilars)
          - [CELL & GENE THERAPY](https://sbhsciences.com/cgt)
          - [SMALL MOLECULE](https://sbhsciences.com/small-molecule)
    - [FTE MODEL](https://sbhsciences.com/fte-model)
    - [CONSULTING](https://sbhsciences.com/mentoring)
- Open submenu for INDICATIONS 
  
    - [NEUROLOGY](https://sbhsciences.com/neurology)
    - [METABOLIC](https://sbhsciences.com/metabolic)
    - [ONCOLOGY](https://sbhsciences.com/oncology)
    - [KIDNEY](https://sbhsciences.com/kidney)
    - [MUSCLE](https://sbhsciences.com/muscle)
- Open submenu for PRODUCTS 
  
    - [CYTOKINES](https://sbhsciences.com/cytokines)
    - [MONOCLONAL ANTIBODIES](https://sbhsciences.com/monoclonal-antibodies)
    - [GLYCOBIOLOGY](https://sbhsciences.com/glycobiology)
- Open submenu for INSIGHTS 
  
    - [NEWS AND BLOG](https://sbhsciences.com/sbh-blog-and-news)
    - [REFERENCES AND PUBLICATIONS](https://sbhsciences.com/references)
    - [STRATEGIC PARTNERSHIPS](https://sbhsciences.com/partnerships)

Search

Search

Search

Search

![Human BMP-2 Recombinant Protein](https://sbhsciences.com/hubfs/Screenshot%202026-01-20%20at%202.06.00%20PM.png)

# *[cancer](https://sbhsciences.com/blog/tag/cancer) | [metabolic](https://sbhsciences.com/blog/tag/metabolic)* Human BMP-2 Recombinant Protein

Catalog #001-HBMP2

 

 

###### Description

 

TGF-β family members are key modulators of cell proliferation, differentiation, matrix synthesis, and apoptosis. As implied by their name, BMPs initiate, promote, and regulate the development, growth and remodeling of bone and cartilage. In addition to this role, BMPs are also involved in prenatal development and postnatal growth, remodeling and maintenance of a variety of other tissues and organs.  BMP-2 is a potent osteoinductive cytokine, capable of inducing bone and cartilage formation in association with an osteoconductive carrier such as collagen and synthetic hydroxyapatite. In addition to its osteogenic activity, BMP-2 appears to play an important role in cardiac morphogenesis, and is expressed in a variety of other tissues, including lung, liver, spleen, prostate, ovary, and small intestine.  The functional form of BMP-2 is a 26 kDa protein composed of two identical 114 amino acid polypeptide chains (monomers) linked by a single disulfide bond. Each BMP-2 monomer is expressed as the C-terminal part of a precursor polypeptide, which also contains a 23 amino acid signal sequence for secretion, and a 259 amino acid propeptide. After dimerization of this precursor, the covalent bonds between the propeptide (which is also a disulfide-linked homodimer) and the mature BMP-2 ligand are cleaved by a furin-type protease.  Recombinant Human BMP-2 derived from CHO cells is a homodimeric glycoprotein that consists of two 114 amino acid polypeptide chains linked by a single disulfide bond.  Due to glycosylation, CHO cell-derived Human BMP-2 migrates at an apparent molecular weight of approximately 28-29 kDa by SDS-PAGE analysis under non-reducing conditions.

 

###### Product Specific Information

 

Storage: Store at -20°C for long-term stability.

| PROPERTIES |  |
| --- | --- |
| Species | Human |
| Expression System | Chinese Hamster Ovary (CHO) Cells |
| Molecular Weight | 26 kDa |
| Full Length | 114 amino acids |
| Purity | ≥95% by SDS-PAGE and HPLC Analyses |
| Form | Lyophilized |
| Endotoxin | \<1 EU/µg |
| Activity | Determined by its ability to induce alkaline phosphatase production by ATDC-5 cells. The expected ED50 for this effect is 1.0 - 2.0 ng/ml |
| Storage | -20°C |

### Sign up for our newsletter!

**Discovery Research Products & Services**  
(508) 650-6218 | [Inquiries@SBHsciences.com](mailto:Inquiries@SBHsciences.com)  
The World's Leading Provider of Cytokine Cell-Based Assays

Recombinant Cytokines, Enzymes, Antibodies, Cell-Based Assay and Innovative Process Development Solutions

**[COMPANY](https://sbhsciences.com/about-sbh)**  
[About Us](https://sbhsciences.com/about-sbh)   
[SBH Leadership](https://sbhsciences.com/sbh-leadership)   
[Company Presentation](https://sbhsciences.com/hubfs/43587181/SBH_Presentation.pdf)  
[Strategic Partnerships](https://sbhsciences.com/partnerships)  
[References and Publications](https://sbhsciences.com/references)  
[News and Blog](https://sbhsciences.com/sbh-blog-and-news)

[Careers](https://sbhsciences.com/careers)  
[Request a Quote](https://sbhsciences.com/contact)  
[Contact Us](https://sbhsciences.com/contact)

**[SERVICES](https://sbhsciences.com/services)**  
[Automated Western Blot](https://sbhsciences.com/platform-technologies#wb)  
[Bioanalytical](https://sbhsciences.com/bioanalytical-discovery-services)  
[Biomarker Testing](https://sbhsciences.com/biomarker-testing)  
[Cell-Based Assay](https://sbhsciences.com/cell-based-assay-services)  
[Cell Culture Services](https://sbhsciences.com/cell-culture-services)  
[Cell & Gene Therapy (CGT)](https://sbhsciences.com/cgt)  
[Small Molecule](https://sbhsciences.com/small-molecule)  
[Biosimilars](https://sbhsciences.com/biosimilars)  
[Antibody Development](https://sbhsciences.com/antibody-development-1)  
[ELISA Services](https://sbhsciences.com/elisa-assays)  
[Molecular Biology](https://sbhsciences.com/molecular-biology-services)  
[Organoids](https://sbhsciences.com/blog/organoids-mini-organs-grown-for-research-and-drug-development)  
[Exosomes](https://sbhsciences.com/exosome-services)  
[Protein Purification/Production](https://sbhsciences.com/protein-production-services)  
[FTE Scientist Model](https://sbhsciences.com/fte-model)  
[Consulting](https://sbhsciences.com/mentoring)

**INDICATIONS**  
[Oncology](https://sbhsciences.com/oncology)  
[Kidney](https://sbhsciences.com/kidney)  
[Muscle](https://sbhsciences.com/muscle)  
[Metabolic](https://sbhsciences.com/metabolic)  
[Neurology](https://sbhsciences.com/neurology)

**[PRODUCTS](https://sbhsciences.com/products)**  
[Request a Quote](https://sbhsciences.com/contact)  
[Cytokines](https://sbhsciences.com/cytokines)  
[Monoclonal Antibodies](https://sbhsciences.com/monoclonal-antibodies)  
[Glycobiology](https://sbhsciences.com/glycobiology)

**[SBH Bioventure](https://sbhsciences.com/sbh-bioventure)**

[**SBH Diagnostics**](https://sbhdiagnostics.com/#)

 

[![linkedin](https://sbhsciences.com/hs-fs/hubfs/Imported%20sitepage%20images/linkedin.gif?width=45&height=44&name=linkedin.gif)](https://www.linkedin.com/company/sbh-sciences)

 

 

©2026 SBH Sciences. All rights reserved. [Terms of Use](https://sbhsciences.com/tou) | [Privacy Policy](https://sbhsciences.com/tou#pp)

```json
{
  "@context" : "https://schema.org",
  "@type" : "BlogPosting",
  "author" : {
    "@type" : "Person",
    "name" : "Cytokines",
    "url" : "https://sbhsciences.com/blog/author/cytokines"
  },
  "dateModified" : "2026-01-22T01:53:17.608Z",
  "datePublished" : "2026-01-20T19:08:17.000Z",
  "headline" : "Human BMP-2 Recombinant Protein",
  "image" : [ "https://sbhsciences.com/hubfs/Screenshot%202026-01-20%20at%202.06.00%20PM.png" ],
  "mainEntityOfPage" : {
    "@id" : "https://sbhsciences.com/blog/human-bmp-2-recombinant-protein",
    "@type" : "WebPage"
  },
  "publisher" : {
    "@type" : "Organization",
    "logo" : {
      "@type" : "ImageObject",
      "url" : "https://sbhsciences.com/hubfs/Imported%20sitepage%20images/sbhlogo.png"
    },
    "name" : "SBH Sciences"
  }
}
```

```json
{
  "@context" : "https://schema.org",
  "@id" : "https://sbhsciences.com/blog/author/cytokines#author",
  "@type" : "Person",
  "email" : null,
  "name" : "Cytokines",
  "sameAs" : [ ]
}
```

```json
{
  "@context" : "https://schema.org",
  "@id" : "https://sbhsciences.com/blog/human-bmp-2-recombinant-protein#blogposting",
  "@type" : "BlogPosting",
  "author" : {
    "@id" : "https://sbhsciences.com/blog/author/cytokines#author"
  },
  "commentCount" : 0,
  "dateModified" : "2024-10-01T12:0000+0000",
  "datePublished" : "2026-01-20T19:0817+0000",
  "headline" : "Human BMP-2 Recombinant Protein",
  "image" : "https://sbhsciences.com/blog/human-bmp-2-recombinant-protein",
  "inLanguage" : "en",
  "keywords" : [ "cancer", "metabolic" ],
  "mainEntityOfPage" : "https://sbhsciences.com/blog/human-bmp-2-recombinant-protein",
  "name" : "Human BMP-2 Recombinant Protein",
  "publisher" : {
    "@id" : "https://www.yourdomain.com#organization"
  },
  "url" : "https://sbhsciences.com/blog/human-bmp-2-recombinant-protein",
  "wordCount" : 284
}
```