--- title: METABOLIC description: translational research for metabolic disease, MASH, diabetes, obesity including functional assays, biomarkers, disease models, hepatic markers, pancreas image: https://sbhsciences.com/hubfs/ChatGPT%20Image%20Jan%2019%2c%202026%2c%2010_57_16%20AM.png --- [![SBH Sciences](https://sbhsciences.com/hs-fs/hubfs/Imported%20sitepage%20images/sbhlogo.png?width=155&height=74&name=sbhlogo.png "SBH Sciences")](https://sbhsciences.com/) - Open submenu for ABOUT US - [ABOUT SBH](https://sbhsciences.com/about-sbh) - [LEADERSHIP](https://sbhsciences.com/sbh-leadership) - [CONTACT](https://sbhsciences.com/contact) - [CAREERS](https://sbhsciences.com/careers) - [SBH BIOVENTURE](https://sbhsciences.com/sbh-bioventure) - [SOLUTIONS](https://sbhsciences.com/services) Show submenu for SOLUTIONS - [CELL BASED ASSAYS](https://sbhsciences.com/cell-based-assay-services) - Open submenu for PRODUCT SERVICES - [PROTEINS](https://sbhsciences.com/protein-production-services) - [MOLECULAR BIOLOGY](https://sbhsciences.com/molecular-biology-services) - 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Open submenu for PRODUCTS - [CYTOKINES](https://sbhsciences.com/cytokines) - [MONOCLONAL ANTIBODIES](https://sbhsciences.com/monoclonal-antibodies) - [GLYCOBIOLOGY](https://sbhsciences.com/glycobiology) - Open submenu for INSIGHTS - [NEWS AND BLOG](https://sbhsciences.com/sbh-blog-and-news) - [REFERENCES AND PUBLICATIONS](https://sbhsciences.com/references) - [STRATEGIC PARTNERSHIPS](https://sbhsciences.com/partnerships) Search Search Search Search ![ChatGPT Image Jan 27, 2026, 03\_59\_01 PM](https://sbhsciences.com/hubfs/ChatGPT%20Image%20Jan%2027%2c%202026%2c%2003_59_01%20PM.png) # Our Translational Research Platform for Metabolic Disease [Talk to an Expert](mailto:ydagon@sbhsciences.com) ## *SBH SCIENCES*Metabolic Disease Research Center *We partner with industry and academic institutions to support drug development across a broad range of metabolic disorders and MASH by providing comprehensive disease modeling* s*tate-of-the-art functional assays,* *and biomarker discovery and development* *services.*   ## Our In-Vitro Models, Biomarker Platforms, and Functional Assays We have developed a platform of functional assays in a growing range of in vitro models to support drug development programs for key indications in metabolic disease drug development including: - Insulin Resistance & Type 2 Diabetes - Obesity & Adipose Dysfunction - Metabolic Syndrome - MASH/MASLD - Advanced MASH & Fibrosis ![ChatGPT Image Jan 27, 2026, 04\_27\_53 PM](https://sbhsciences.com/hs-fs/hubfs/ChatGPT%20Image%20Jan%2027%2c%202026%2c%2004_27_53%20PM.png?width=1536&height=1024&name=ChatGPT%20Image%20Jan%2027%2c%202026%2c%2004_27_53%20PM.png "ChatGPT Image Jan 27, 2026, 04_27_53 PM") ![Screenshot 2026-01-27 at 5-31-02 PM-1-1](https://sbhsciences.com/hubfs/Screenshot%202026-01-27%20at%205-31-02%20PM-1-1.png) **3T3-L1 Preadipocytes/** **Adipocytes** - Adipocyte Differentiation (Adipogenesis) Assay​ - Insulin-Stimulated Glucose Uptake Assay​ - Lipolysis and Lipid Mobilization Assay​ - Adipokine Secretion Profiling​ - Mitochondrial Function & Energy Metabolism Assay​ - Inflammation-Induced Insulin Resistance Assay ![Screenshot 2026-01-27 at 5-33-59 PM](https://sbhsciences.com/hubfs/Screenshot%202026-01-27%20at%205-33-59%20PM.png) ### Hepatocytes (primary & cell lines) - Hepatotoxicity & Cellular Stress Response​ - 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