Description : |
Interleukin-12 is a disulfide-linked heterodimeric protein (p70), composed of two subunits, p35 and p40, which are encoded by two different genes. Accumulating data indicate that p40 secretion precedes that of IL-12 expression. In addition, to its ability to covalently bind to p35 to form IL-12, p40 can bind to p19 to form IL-23. Recombinant human IL-12 p40 is a 40 kDa protein containing 306 amino acid residues.
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Catalog #: |
001-HIL12P40 |
Source : |
CHO cells (Chinese Hamster Ovarian cells) |
Formulation : |
Sterile filtered and then the protein was lyophilized in 1 x PBS pH 6.8. |
Stability : |
The lyophilized protein is stable for a few weeks at room temperature, but best stored at -800C.
Reconstituted IL-12 p40 should be stored in working aliquots at -800C. |
Purity : |
Greater than 97% by SDS-PAGE and HPLC analysis. Endotoxin level is less than 0.1 ng per μg (1EU/μg). |
Reconstitution : |
We recommend a quick spin followed by reconstitution in 200 ul of sterile water for injection for 0.5 mg/ml concentration .
This solution can then be diluted into other aqueous buffers and stored at 40C for 3 months or below -100C for future use.
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Biological Activity : |
Human IL-12 p40 has no IL-12 (p70) antagonist activity. |
PubMed Link : |
IL-12 p40 Human |
Usage: |
For research only. Not for use in diagnostic or therapeutic procedures. |
Country of Origin : |
USA |
