Cell-Based Assay Services
Comprehensive, Functional Analysis of Cytokines and Chemokines
Bioassays designed to characterize cytokine activity, assess functional potency, and support therapeutic development across human and preclinical species.
360+ Validated Bioassays. Custom Assays Delivered in Under 2 Weeks.

What We Offer
Custom Bioassay Development
360+ Validated Cell-Based Assays
Cell-Based Compound Screening
Evaluate compounds and therapeutic candidates using functional cellular models, with access to 500+ mammalian cell lines, including 400+ human cancer cell lines.
Popular Human Cytokine Assays We Offer
-
Human Activin A
-
Human BAFF
-
Human BDNF (Brain-Derived Neurotrophic Factor)
-
Human BMP-4 (Bond Morphogenetic Protein)
-
Human b-NGF (Beta-Nerve Growth Factor)
-
Human C5a
-
Human CD40L
-
Human Chitinase-3-like
-
Human CTGF (Connective Tissue Growth Factor)
-
Human EGF (Epidermal Growth Factor)
-
Human FGF-Basic (Fibroblast Growth Factor)
-
Human Fibronectin
-
Human FLT3 Ligand
-
Human GDNF (Glial cell line-Derived Neurotrophic
-
Factor)
-
Human GM-CSF
-
Human Heregulin B1
-
Human HGF (Hepatocyte Growth Factor)
-
Human IFNb (Interferon Beta)
-
Human IFNy
-
Human IGF-I (Insuline-like Growth Factor)
-
Human IL-2
-
Human IL-3
-
Human IL-4
-
Human IL-6
-
Human IL-7
-
Human IL-8
-
Human IL-10
-
Human IL-11
-
Human IL-12
-
Human IL-13
-
Human IL-15
-
Human IL-33
-
Human IL-36
-
Human KGF (Keratinocyte Growth Factor)
-
Human LAG-3 (Lymphocyte-activation gene 3)
-
Human LIF (Leukemia Inhibitory Factor)
-
Human M-CSF (Macrophage Colony-Stimulating Factor)
-
Human Myostatin
-
Human Myostatin Propeptide
-
Human Noggin
-
Human NT-3 (Neurotrophin-3)
-
Human Oncostatin M
-
Human Osteopontin
-
Human PDGF-BB (Platelet-Derived Growth Factor)
-
Human SCF (Stem Cell Factor)
-
Human SHH (Sonic Hedgehog)
-
Human TGF-alpha
-
Human TGF-b1 (Transforming Growth Factor-Beta)
-
Human TL1A
-
Human TNF-a (Tumor Necrosis Factor-alpha)
-
Human TPO (Thrombopoietin)
-
Human VEGF (Vascular Endothelial Growth Factor)
-
Human VItronectin
-
Human Wnt-1
-
Human IL-17A
-
Human IL-18
-
Human IL-19
-
Human IL-20
-
Human IL-21
-
Human IL-22
-
Human IL-23
What Cell-Based Assays Can Measure
From target validation to lead optimization.

Cell Phenotyping
Proliferation
Cytotoxicity
Cell Migration & Invasion
Phagocytosis
Immune Function
T-Cell Activation
PBMC Stimulation
Microglial Activation
Phagocytosis
Complement-Dependent Cytotoxicity (CDC)
Antibody-Dependent Cellular Cytotoxicity (ADCC)
Antibodies & Biologics
Neutralizing Antibody Assays
Anti-Drug Antibody (ADA) Assays
BiTE (Bi-Specific T-Cell Engager) Assays
Antibody Drug Conjugate (ADC) Assays
Target Engagement
Agonist/Antagonist Screening
Receptor-Ligand Binding Assays
GPCR Activation Assays
Chemokine Functional Assays (GPCR-Based)
Biomarkers & Proteins
Immunoassays
Lumit™ Immunoassays
Cytokine Release Assays
Custom Bioassay Development
At SBH Sciences, we are continually developing new assays for our customers and would be pleased to include additional ones at your request. We can assure strict confidentiality and superior execution which will be delivered in a time and cost effective manner. The expected turnaround time per assay is less than two weeks, and includes a written report containing methods, results, and conclusions. SBH Sciences is determined to maintain the highest standards and deliver the highest quality products and services. We welcome your suggestions and encourage you to communicate with us about your individual research requirements.
When the need arises to analyze the activity of novel compounds or neutralization capability of your antibody or receptor, please contact us. It will be our pleasure to assist you.
Cytokine & Chemokine Assays Currently Available at SBH
|
Cytokine |
Human |
Murine |
Rat |
Bovine |
|---|---|---|---|---|
|
4-1BBL |
+ (data) |
|
|
|
|
Activin A |
+ (data) |
+ |
+ |
|
|
Activin B |
+ (data) |
|
|
|
|
Adipolean / gArcp30 |
+ (data) |
+ |
|
|
|
Adiponectin |
+ |
|
|
|
|
AITRL |
+ (data) |
|
|
|
|
Amphiregulin |
+ (data) |
+ (data) |
|
|
|
APRIL |
+ |
|
|
|
|
ApoE2 |
+ (data) |
|
|
|
|
ApoE3 |
+ (data) |
|
|
|
|
ApoE4 |
+(data) |
|
|
|
|
ANG-1 |
+ |
|
|
|
|
Artemin |
+ |
+ (data) |
|
|
|
B7-1 |
|
+ |
|
|
|
BAFF |
+ (data) |
|
|
|
|
BAFF- Receptor |
+ (data) |
|
|
|
|
BDNF |
+ (data) |
+ (data) |
+ (data) |
|
|
Betacellulin |
+ |
+ |
|
|
|
BMP-2 |
+ |
+ |
+ |
|
|
BMP-3 |
+ |
|
|
|
|
BMP-4 |
+ (data) |
+ |
|
|
|
BMP-5 |
+ |
|
|
|
|
BMP-6 |
+ (data) |
|
|
|
|
BMP-7 |
+ (data) |
+ (data) |
+ (data) |
|
|
BMP-9 / GDF-2 |
+ |
|
|
|
|
BMP-10 |
+ |
|
|
|
|
BMP-13 / CDMP-2 / GDF-6 |
+ |
|
|
|
|
BMP-14 / CDMP-1 / GDF-5 |
+ |
+ |
|
|
|
Cardiotrophin-1 |
+ |
+ |
|
|
|
CD22 |
+ |
|
|
|
|
CD30 Ligand |
+ |
|
|
|
|
CD40 Ligand |
+ (data) |
|
|
|
|
Chemerin |
+ |
|
|
|
|
COCO |
+ |
|
|
|
|
CNTF |
+ |
|
+ |
|
|
CTGF |
+ |
|
|
|
|
CTGFL / WISP-2 |
+ |
|
|
|
|
CYR61 |
+ |
|
|
|
|
DHH (Desert Hedgehog) |
+ |
|
|
|
|
DKK-1 |
+ |
|
|
|
|
EG-VEGF |
+ |
+ |
|
|
|
EGF |
+ (data) |
+ (data) |
+ |
|
|
EGF-R-Fc |
+ |
|
|
|
|
EMAP-II |
+ |
|
|
|
|
Endostatin |
+ |
|
|
|
|
Epigen |
+ (data) |
|
|
|
|
Epiregulin |
+ |
|
|
|
|
EPO |
+ (data) |
+ (data) |
|
|
|
Fas |
+ |
|
|
|
|
Fas-Ligand |
+ (data) |
|
|
|
|
FGF-acidic |
+ |
+ |
|
|
|
FGF-basic |
+ (data) |
+ (data) |
+ (data) |
+ (data) |
|
FGF-4 |
+ (data) |
|
|
|
|
FGF-5 |
+ (data) |
|
|
|
|
FGF-6 |
+ (data) |
|
|
|
|
FGF-7 / KGF |
+ (data) |
+ |
|
|
|
FGF-8 |
+ (data) |
|
|
|
|
FGF-8a |
+(data) |
|
|
|
|
FGF-9 |
+ (data) |
+ |
|
|
|
FGF-10 |
+ |
|
|
|
|
FGF-16 |
+ (data) |
|
|
|
|
FGF-17 |
+ |
|
|
|
|
FGF-18 |
+ (data) |
|
|
|
|
FGF-19 |
+ (data) |
|
|
|
|
FGF-20 |
+ |
|
|
|
|
FGF-21 |
+ (data) |
|
|
|
|
FGF-23 |
+ (data) |
+ |
|
|
|
FGF-R1 / Fc Chimera |
+ |
|
|
|
|
FGF-R4 / Fc Chimera |
+ |
|
|
|
|
Fibronectin |
+ |
|
|
|
|
Flt3/ Fc Chimera |
+ |
|
|
|
|
Flt3-Ligand |
+ (data) |
+ (data) |
|
|
|
Follistatin |
+ |
|
|
|
|
Fractalkine |
+ |
|
+ |
|
|
sFRP-1 |
+ |
|
|
|
|
G-CSF |
+ (data) |
+ |
+ |
|
|
Galectin-3 |
+ |
|
|
|
|
GASP-1 |
+ |
|
|
|
|
GDF-3 |
+ |
|
|
|
|
GDF-9 |
+ |
|
|
|
|
GDF-9B |
+ |
|
|
|
|
GDF-11 |
+ (data) |
|
|
|
|
GDNF |
+ (data) |
+ (data) |
+ (data) |
|
|
GH (Growth Hormone) |
+ (data) |
|
|
|
|
GM-CSF |
+ (data) |
+(data) |
+ |
+ |
|
Gremlin-1 |
+ (data) |
|
|
|
|
GRO-alpha / MGSA (CXCL1) |
+ |
|
|
|
|
GRO-beta |
+ |
|
|
|
|
GRO-gamma |
+ |
|
|
|
|
GRO-KC |
|
|
+ |
|
|
HB-EGF |
+ (data) |
|
|
|
|
Heregulin-beta 1 |
+ (data) |
|
|
|
|
HGF |
+ (data) |
+ |
|
|
|
HVEM-Fc |
+ |
|
|
|
|
IFN-a |
+ (data) |
+ |
|
|
|
IFN-a -R2-FC |
+ |
|
|
|
|
IFN-b |
+ (data) |
|
|
|
|
IFN-g |
+ (data) |
+ |
|
+ |
|
IFN-g-RII |
+ |
|
|
|
|
IFN-ω |
+ (data) |
|
|
|
|
IGF-I |
+ (data) |
+ (data) |
+ |
|
|
IGF-II |
+ (data) |
|
|
|
|
IGF-Binding Protein 1 |
+ |
|
|
|
|
IGF-Binding Protein 2 |
+ (data) |
|
|
|
|
IGF-Binding Protein 3 |
+ (data) |
|
|
|
|
IGF-Binding Protein 4 |
+ |
|
|
|
|
IGF-Binding Protein 5 |
+ |
|
|
|
|
IGF-Binding Protein 6 |
+ (data) |
|
|
|
|
IGF-Binding Protein 7 |
+ |
|
|
|
|
IL-1a |
+ (data) |
+ |
+ |
|
|
IL-1b |
+ (data) |
+ |
+ |
+ |
|
IL-1-Receptor Antagonist |
+ |
|
|
|
|
IL-1-sReceptor II |
+ |
|
|
|
|
IL-2 |
+ (data) |
+ |
+ |
|
|
s-IL-2 Receptor alpha |
+ |
|
|
|
|
IL-2R Beta |
+ |
|
|
|
|
IL-3 |
+ (data) |
+ (data) |
+ |
|
|
s-IL-3 Receptor alpha |
+ |
|
|
|
|
IL-4 |
+ (data) |
+ |
+ |
+ |
|
s-IL-4 Receptor alpha |
+ |
|
|
|
|
IL-5 |
+ (data) |
+ (data) |
+ |
|
|
s-IL-5 Receptor alpha |
+ |
|
|
|
|
IL-6 |
+ (data) |
+ |
+ |
|
|
s-IL-6 Receptor |
+ |
|
|
|
|
IL-7 |
+ (data) |
+ |
+ |
|
|
IL-7-R alpha / Fc Chimera |
+ |
|
|
|
|
IL-8 |
+ |
|
|
|
|
IL-9 |
+ (data) |
+ |
|
|
|
IL-10 |
+ (data) |
+ |
+ |
|
|
IL-10 Receptor alpha |
+ |
|
|
|
|
IL-11 |
+ (data) |
+ |
|
|
|
IL-12 p70 |
+ |
+ |
+ |
|
|
IL-12 p80 |
|
+ |
|
|
|
IL-13 |
+ (data) |
+ |
+ |
+ |
|
IL-15 |
+ (data) |
+(data) |
+ |
|
|
IL-16 |
+ |
+ |
|
|
|
IL-17 |
+ |
+ |
|
|
|
IL-17B |
+ |
|
|
|
|
IL-17D |
+ |
|
|
|
|
IL-17E |
|
+ |
|
|
|
IL-17F |
+ |
|
|
|
|
IL-18 |
+ |
+ |
|
|
|
IL-18-BPa / Fc Chimera |
+ |
|
|
|
|
IL-19 |
+ |
|
|
|
|
IL-20 |
+ |
|
|
|
|
IL-21 |
+ (data) |
+ |
|
|
|
IL-22 |
+ |
+ |
|
|
|
IL-22BP |
+ |
|
|
|
|
IL-23 |
+ (data) |
+ |
|
|
|
IL-24 |
+ |
|
|
|
|
IL-27 |
+ (data) |
|
|
|
|
IL-33 |
+ (data) |
+ |
|
|
|
IL-35 |
+ |
|
|
|
|
IL-36 beta |
+ |
+ |
|
|
|
IL-36 gamma |
+ |
|
|
|
|
Insulin |
+ (data) |
|
|
+ |
|
IP-10 |
+ |
|
|
|
|
Klotho |
+ (data) |
+ |
|
|
|
LAG-3 |
+ |
|
|
|
|
Leptin |
+ |
+ |
+ |
|
|
LIF |
+ (data) |
+ (data) |
|
|
|
LIGHT |
+ |
+ |
|
|
|
M-CSF |
+ (data) |
+ |
+ |
|
|
Maspin |
+ |
|
|
|
|
MCP-1 |
+ |
|
|
|
|
MCP-2 |
+ |
|
|
|
|
MCP-3 |
+ |
|
|
|
|
MCP-4 |
+ |
|
|
|
|
MIA |
+ |
|
|
|
|
MIC-1 / GDF-15 |
+ |
|
|
|
|
MIF |
+ |
|
|
|
|
MIP-1 alpha |
+ |
|
|
|
|
MIP-2 |
|
+ |
|
|
|
Myostatin |
+ (data) |
+ |
|
|
|
Myostatin-Propeptide |
+ (data) |
+ |
|
|
|
Nanog |
+ |
|
|
|
|
Neuropoietin |
|
+ |
|
|
|
Neuroserpin |
+ (data) |
+ |
|
|
|
Neurturin |
+ |
|
|
|
|
b-NGF |
+ (data) |
+ (data) |
|
|
|
NGF-Receptor / Fc Chimera |
+ |
|
|
|
|
Noggin |
+ (data) |
+ (data) |
|
|
|
NOV |
+ (data) |
|
|
|
|
NT-3 |
+ |
|
|
|
|
NT-4 |
+ |
|
|
|
|
Oncostatin M |
+ (data) |
|
|
|
|
OTOR |
+ |
|
|
|
|
OX40-Ligand |
+ |
|
|
|
|
PDGF-AA |
+ (data) |
+ |
|
|
|
PDGF-AB |
+ (data) |
|
|
|
|
PDGF-BB |
+ (data) |
|
|
|
|
PDGF-CC |
+ (data) |
|
|
|
|
PDGF-DD |
+ |
|
|
|
|
PF-4 |
+ |
|
|
|
|
Persephin |
|
+ |
|
|
|
Prokineticin-2 |
+ |
|
|
|
|
R-Spondin-1 |
+ (data) |
+ |
|
|
|
R-Spondin-2 |
+ |
|
|
|
|
R-Spondin-3 |
+ |
|
|
|
|
RANK Ligand |
|
+ |
|
|
|
SCF |
+ (data) |
+ (data) |
+ |
|
|
SCGF-A |
+ |
+ |
+ |
|
|
SCGF-B |
+ |
+ |
+ |
|
|
Sonic Hedgehog |
+ (data) |
+ |
|
|
|
SOST-1 |
+ |
|
|
|
|
TGF-a |
+ (data) |
|
|
|
|
TGF-b1 |
+ (data) |
|
|
|
|
TGF-b-RI |
+ |
|
|
|
|
TGF-b-RII |
+ |
|
|
|
|
TGF-b2 |
+ (data) |
|
|
|
|
TGF-b3 |
+ (data) |
|
|
|
|
TL-1A |
+ |
+
|
|
|
|
TNF-a |
+ (data) |
+ |
+ |
+ |
|
TNF-b |
+ (data) |
|
|
|
|
sTNF- r I |
+ |
|
|
|
|
sTNF-r II |
+ (data) |
|
|
|
|
TPO |
+ (data) |
+ (data) |
|
|
|
Trail / Apo2 Ligand |
+ |
|
|
|
|
sTrail Receptor-1 |
+ |
|
|
|
|
sTrail Receptor-2 |
+ |
|
|
|
|
TrkA / Fc Chimera |
+ |
|
|
|
|
Tweak |
+ (data) |
|
|
|
|
Tweak Receptor |
+ |
|
|
|
|
Twisted Gastrulation (TSG) |
+ (data) |
+ |
|
|
|
USAG-1 |
+ |
|
|
|
|
VEGF - 121 |
+ (data) |
|
|
|
|
VEGF - 165 |
+ (data) |
+ |
+ |
|
|
VEGF - B |
+ (data) |
|
|
|
|
VEGF - C |
+ (data) |
|
|
|
|
VEGF - D |
+ |
|
|
|
|
Visfatin |
+ (data) |
|
|
|
|
Vitronectin |
+ |
|
|
|
|
WIF-1 |
+ |
|
|
|
|
WISP-1 |
+ |
|
|
|
|
WISP-3 |
+ |
|
|
|
|
WNT-1 |
+ |
|
|
|
|
WNT-3A |
+ (data) |
+ (data) |
|
|
|
WNT-5A |
+ |
|
|
|
|
WNT-7A |
+ (data) |
|
|
|
|
WNT-9A |
+ (data) |
|
|
|
If you need a bioassay that is not currently available on our list,
please contact us, and we will be happy to assist you.
We Offer the Most Comprehensive Cytokine and Chemokine Assay Capabilities Worldwide
Most of these assays employ a colorimetric method of measuring cell activity using a non-radioactive substrate, which is equivalent to the 3H-thymidine incorporation assay*.
With diverse experience in large molecule, we are routinely developing new cell-based assays for our customers. We assure strict confidentiality, superior execution, competitive pricing, and a quick turnaround time. The average timeframe for an established assay is few weeks. SBH Sciences is determined to maintain the highest standards and deliver quality products and services. We welcome your suggestions and encourage you to communicate with us about your specific cell-based assay and research requirements.
*Cell Signaling Applications Guide, Promega Corporation
