Cell-Based Assay Services

 

Comprehensive, Functional Analysis of Cytokines and Chemokines

Bioassays designed to characterize cytokine activity, assess functional potency, and support therapeutic development across human and preclinical species.

360+ Validated Bioassays. Custom Assays Delivered in Under 2 Weeks. 

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What We Offer

Popular Human Cytokine Assays We Offer

  • Human Activin A

  • Human BAFF

  • Human BDNF (Brain-Derived Neurotrophic Factor)

  • Human BMP-4 (Bond Morphogenetic Protein)

  • Human b-NGF (Beta-Nerve Growth Factor)

  • Human C5a

  • Human CD40L

  • Human Chitinase-3-like

  • Human CTGF (Connective Tissue Growth Factor)

  • Human EGF (Epidermal Growth Factor)

  • Human FGF-Basic (Fibroblast Growth Factor)

  • Human Fibronectin

  • Human FLT3 Ligand

  • Human GDNF (Glial cell line-Derived Neurotrophic

  • Factor)

  • Human GM-CSF

  • Human Heregulin B1

  • Human HGF (Hepatocyte Growth Factor)

  • Human IFNb (Interferon Beta)

  • Human IFNy

  • Human IGF-I (Insuline-like Growth Factor)

  • Human IL-2

  • Human IL-3

  • Human IL-4

  • Human IL-6

  • Human IL-7

  • Human IL-8

  • Human IL-10

  • Human IL-11

  • Human IL-12 

  • Human IL-13

  • Human IL-15

  • Human IL-33

  • Human IL-36

  • Human KGF (Keratinocyte Growth Factor)

  • Human LAG-3 (Lymphocyte-activation gene 3)

  • Human LIF (Leukemia Inhibitory Factor)

  • Human M-CSF (Macrophage Colony-Stimulating Factor)

  • Human Myostatin

  • Human Myostatin Propeptide

  • Human Noggin

  • Human NT-3 (Neurotrophin-3)

  • Human Oncostatin M

  • Human Osteopontin

  • Human PDGF-BB (Platelet-Derived Growth Factor)

  • Human SCF (Stem Cell Factor)

  • Human SHH (Sonic Hedgehog)

  • Human TGF-alpha

  • Human TGF-b1 (Transforming Growth Factor-Beta)

  • Human TL1A

  • Human TNF-a (Tumor Necrosis Factor-alpha)

  • Human TPO (Thrombopoietin)

  • Human VEGF (Vascular Endothelial Growth Factor)

  • Human VItronectin

  • Human Wnt-1 

  • Human IL-17A

  • Human IL-18

  • Human IL-19

  • Human IL-20

  • Human IL-21

  • Human IL-22

  • Human IL-23 

What Cell-Based Assays Can Measure

From target validation to lead optimization. 

cell_based_assays_linear-1-1

Cell Phenotyping

Proliferation

Cytotoxicity

Cell Migration & Invasion

Phagocytosis

 

 

 

Immune Function

T-Cell Activation

PBMC Stimulation

Microglial Activation

Phagocytosis

Complement-Dependent Cytotoxicity (CDC)

Antibody-Dependent Cellular Cytotoxicity (ADCC)

 

 

 

Antibodies & Biologics

Neutralizing Antibody Assays

Anti-Drug Antibody (ADA) Assays

BiTE (Bi-Specific T-Cell Engager) Assays

Antibody Drug Conjugate (ADC) Assays

 

 

 

Target Engagement

Agonist/Antagonist Screening

Receptor-Ligand Binding Assays

GPCR Activation Assays

Chemokine Functional Assays (GPCR-Based)

 

 

 

Biomarkers & Proteins

Immunoassays

Lumit™ Immunoassays

Cytokine Release Assays

 

 

 

Custom Bioassay Development

At SBH Sciences, we are continually developing new assays for our customers and would be pleased to include additional ones at your request. We can assure strict confidentiality and superior execution which will be delivered in a time and cost effective manner. The expected turnaround time per assay is less than two weeks, and includes a written report containing methods, results, and conclusions. SBH Sciences is determined to maintain the highest standards and deliver the highest quality products and services. We welcome your suggestions and encourage you to communicate with us about your individual research requirements.

When the need arises to analyze the activity of novel compounds or neutralization capability of your antibody or receptor, please contact us. It will be our pleasure to assist you.

 

Cytokine & Chemokine Assays Currently Available at SBH

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No assays found for "". Contact us to request a custom assay.

 

Cytokine

Human

Murine

Rat

Bovine

4-1BBL

+ (data) 

 
 
 

Activin A

+ (data)

+

+

 

Activin B

+ (data)

 
 
 

Adipolean / gArcp30

+ (data)

+

 
 

Adiponectin

+

 
 
 

AITRL

+ (data)

 
 
 

Amphiregulin

+ (data)

+ (data)

 
 

APRIL

+

 
 
 

ApoE2

+ (data)

 
 
 

ApoE3

+ (data)

 
 
 

ApoE4

+(data)

 
 
 

ANG-1

+

 
 
 

Artemin

+

+ (data)

 
 

B7-1

 

+

 
 

BAFF

+ (data)

 
 
 

BAFF- Receptor

+ (data)

 
 
 

BDNF

+ (data)

+ (data)

+ (data)

 

Betacellulin

+

+

 
 

BMP-2

+

+

+

 

BMP-3

+

 
 
 

BMP-4

+ (data)

+

 
 

BMP-5

+

 
 
 

BMP-6

+ (data)

 
 
 

BMP-7

+ (data)

+ (data)

+ (data)

 

BMP-9 / GDF-2

+

 
 
 

BMP-10

+

 
 
 

BMP-13 / CDMP-2 / GDF-6

+

 
 
 

BMP-14 / CDMP-1 / GDF-5

+

+

 
 

Cardiotrophin-1

+

+

 
 

CD22

+

 

 

 

CD30 Ligand

+

 

 

 

CD40 Ligand

+ (data)

 

 

 

Chemerin

+

 
 
 

COCO

+

 
 
 

CNTF

+

 

+

 

CTGF

+

 

 

 

CTGFL / WISP-2

+

 
 
 

CYR61

+

 
 
 

DHH (Desert Hedgehog)

+

 
 
 

DKK-1

+

 
 
 

EG-VEGF

+

+

 
 

EGF

+ (data)

+ (data)

+

 

EGF-R-Fc

+

 
 
 

EMAP-II

+

 
 
 

Endostatin

+

 
 
 

Epigen

+ (data)

 
 
 

Epiregulin

+

 
 
 

EPO

+ (data)

+ (data)

 
 

Fas

+

 
 
 

Fas-Ligand

+ (data)

 
 
 

FGF-acidic

+

+

 
 

FGF-basic

+ (data)

+ (data)

+ (data)

+ (data)

FGF-4

+ (data)

 
 
 

FGF-5

+ (data)

 
 
 

FGF-6

+ (data)

 
 
 

FGF-7 / KGF

+ (data)

+

 
 

FGF-8

+ (data)

 
 
 

FGF-8a

+(data)

 
 
 

FGF-9

+ (data)

+

 
 

FGF-10

+

 
 
 

FGF-16

+ (data)

 
 
 

FGF-17

+

 
 
 

FGF-18

+ (data)

 
 
 

FGF-19

+ (data)

 
 
 

FGF-20

+

 
 
 

FGF-21

+ (data)

 
 
 

FGF-23

+ (data)

+

 
 

FGF-R1 / Fc Chimera

+

 
 
 

FGF-R4 / Fc Chimera

+

 
 
 

Fibronectin

+

 
 
 

Flt3/ Fc Chimera

+

 
 
 

Flt3-Ligand

+ (data)

+ (data)

 
 

Follistatin

+

 
 
 

Fractalkine

+

 

+

 

sFRP-1

+

 
 
 

G-CSF

+ (data)

+

+

 

Galectin-3

+

 
 
 

GASP-1

+

 
 
 

GDF-3

+

 
 
 

GDF-9

+

 
 
 

GDF-9B

+

 
 
 

GDF-11

+ (data)

 
 
 

GDNF

+ (data)

+ (data)

+ (data)

 

GH (Growth Hormone)

+ (data)

 
 
 

GM-CSF

+ (data)

+(data)

+

+

Gremlin-1

+ (data)

 
 
 

GRO-alpha / MGSA (CXCL1)

+

 
 
 

GRO-beta

+

 
 
 

GRO-gamma

+

 
 
 

GRO-KC

 
 

+

 

HB-EGF

+ (data)

 
 
 

Heregulin-beta 1

+ (data)

 
 
 

HGF

+ (data)

+

 
 

HVEM-Fc

+

 
 
 

IFN-a

+ (data)

+

 
 

IFN-a -R2-FC 

+

 
 
 

IFN-b

+ (data)

 
 
 

IFN-g

+ (data)

+

 

+

IFN-g-RII

+

 
 
 

IFN-ω

+ (data)

 
 
 

IGF-I

+ (data)

+ (data)

+

 

IGF-II

+ (data)

 
 
 

IGF-Binding Protein 1

+

 
 
 

IGF-Binding Protein 2

+ (data)

 
 
 

IGF-Binding Protein 3

+ (data)

 
 
 

IGF-Binding Protein 4

+

 
 
 

IGF-Binding Protein 5

+

 
 
 

IGF-Binding Protein 6

+ (data)

 
 
 

IGF-Binding Protein 7

+

 
 
 

IL-1a

+ (data)

+

+

 

IL-1b

+ (data)

+

+

+

IL-1-Receptor Antagonist

+

 
 
 

IL-1-sReceptor II

+

 
 
 

IL-2

+ (data)

+

+

 

s-IL-2 Receptor alpha

+

 
 
 

IL-2R Beta

+

 
 
 

IL-3

+ (data)

+ (data)

+

 

s-IL-3 Receptor alpha

+

 
 
 

IL-4

+ (data)

+

+

+

s-IL-4 Receptor alpha

+

 
 
 

IL-5

+ (data)

+ (data)

+

 

s-IL-5 Receptor alpha

+

 
 
 

IL-6

+ (data)

+

+

 

s-IL-6 Receptor

+

 
 
 

IL-7

+ (data)

+

+

 

IL-7-R alpha / Fc Chimera

+

 

 
 

IL-8

+

 
 
 

IL-9

+ (data)

+

 
 

IL-10

+ (data)

+

+

 

IL-10 Receptor alpha

+

 

 
 

IL-11

+ (data)

+

 
 

IL-12 p70

+

+

+

 

IL-12 p80

 

+

 
 

IL-13

+ (data)

+

+

+

IL-15

+ (data)

+(data)

+

 

IL-16

+

+

 
 

IL-17

+

+

 
 

IL-17B

+

 
 
 

IL-17D

+

 
 
 

IL-17E

 

+

 
 

IL-17F

+

 
 
 

IL-18

+

+

 
 

IL-18-BPa / Fc Chimera

+

 
 
 

IL-19

+

 
 
 

IL-20

+

 
 
 

IL-21

+ (data)

+

 
 

IL-22

+

+

 
 

IL-22BP

+

 
 
 

IL-23

+ (data)

+

 
 

IL-24

+

 
 
 

IL-27

+ (data)

 
 
 

IL-33

+ (data)

+

 
 

IL-35

+

 
 
 

IL-36 beta

+

+

 
 

IL-36 gamma

+

 
 
 

Insulin

+ (data)

 
 

+

IP-10

+

 
 
 

Klotho

+ (data)

+

 
 

LAG-3

+

 
 
 

Leptin

+

+

+

 

LIF

+ (data)

+ (data)

 
 

LIGHT

+

+

 
 

M-CSF

+ (data)

+

+

 

Maspin

+

 
 
 

MCP-1

+

 
 
 

MCP-2

+

 
 
 

MCP-3

+

 
 
 

MCP-4

+

 
 
 

MIA

+

 
 
 

MIC-1 / GDF-15

+

 
 
 

MIF

+

 
 
 

MIP-1 alpha

+

 
 
 

MIP-2

 

+

 
 

Myostatin

+ (data)

+

 
 

Myostatin-Propeptide

+ (data)

+

 
 

Nanog

+

 
 
 

Neuropoietin

 

+

 
 

Neuroserpin

+ (data)

+

 
 

Neurturin

+

 
 
 

b-NGF

+ (data)

+ (data)

 
 

NGF-Receptor / Fc Chimera

+

 
 
 

Noggin

+ (data)

+ (data)

 
 

NOV

+ (data)

 
 
 

NT-3

+

 
 
 

NT-4

+

 
 
 

Oncostatin M

+ (data)

 
 
 

OTOR

+

 
 
 

OX40-Ligand

+

 
 
 

PDGF-AA

+ (data)

+

 
 

PDGF-AB

+ (data)

 
 
 

PDGF-BB

+ (data)

 
 
 

PDGF-CC

+ (data)

 
 
 

PDGF-DD

+

 
 
 

PF-4

+

 
 
 

Persephin

 

+

 
 

Prokineticin-2

+

 
 
 

R-Spondin-1

+ (data)

+

 
 

R-Spondin-2

+

 
 
 

R-Spondin-3

+

 
 
 

RANK Ligand

 

+

 
 

SCF

+ (data)

+ (data)

+

 

SCGF-A

+

+

+

 

SCGF-B

+

+

+

 

Sonic Hedgehog

+ (data)

+

 
 

SOST-1

+

 
 
 

TGF-a

+ (data)

 
 
 

TGF-b1

+ (data)

 
 
 

TGF-b-RI

+

 
 
 

TGF-b-RII

+

 
 
 

TGF-b2

+ (data)

 
 
 

TGF-b3

+ (data)

 
 
 

TL-1A

+

+
 
 

TNF-a

+ (data)

+

+

+

TNF-b

+ (data)

 
 
 

sTNF- r I

+

 
 
 

sTNF-r II

+ (data)

 
 
 

TPO

+ (data)

+ (data)

 
 

Trail / Apo2 Ligand

+

 
 
 

sTrail Receptor-1

+

 
 
 

sTrail Receptor-2

+

 
 
 

TrkA / Fc Chimera

+

 
 
 

Tweak

+ (data)

 
 
 

Tweak Receptor

+

 
 
 

Twisted Gastrulation (TSG)

+ (data)

+

 
 

USAG-1

+

 
 
 

VEGF - 121

+ (data)

 
 
 

VEGF - 165

+ (data)

+

+

 

VEGF - B

+ (data)

 
 
 

VEGF - C

+ (data)

 
 
 

VEGF - D

+

 
 
 

Visfatin

+ (data)

 
 
 

Vitronectin

+

 
 
 

WIF-1

+

 
 
 

WISP-1

+

 
 
 

WISP-3

+

 
 
 

WNT-1

+

 
 
 

WNT-3A

+ (data)

+ (data)

 
 

WNT-5A

+

 
 
 

WNT-7A

+ (data)

 
 
 

WNT-9A

+ (data)

 
 
 

If you need a bioassay that is not currently available on our list,
please contact us, and we will be happy to assist you.

 


We Offer the Most Comprehensive Cytokine and Chemokine Assay Capabilities Worldwide

Most of these assays employ a colorimetric method of measuring cell activity using a non-radioactive substrate, which is equivalent to the 3H-thymidine incorporation assay*.

With diverse experience in large molecule, we are routinely developing new cell-based assays for our customers. We assure strict confidentiality, superior execution, competitive pricing, and a quick turnaround time. The average timeframe for an established assay is few weeks. SBH Sciences is determined to maintain the highest standards and deliver quality products and services. We welcome your suggestions and encourage you to communicate with us about your specific cell-based assay and research requirements.

 

*Cell Signaling Applications Guide, Promega Corporation