Biomarker Assays
Single and multiplex assays for every step of drug development and over 650 analytes. SBH supports a wide range of biomarker testing using Luminex, Ella, and MSD platforms. While only select panels are highlighted below for your convenience, we can run virtually any commercially available kit and customize panels to meet specific research needs. Or we can start from scratch and build your own custom panel.
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Luminex® Multiplex Assays
Broad Spectrum Panels for Research Applications
Select each tab to see the full list of analytes included in each panel
Human Biomarker Panel
| BAFF/BLyS/TNFSF13B | CXCL13/BLC/BCA-1 |
| CCL20/MIP-3 alpha | IL-6R alpha |
| CD14 | TNF RII/TNFRSF1B |
| CD25/IL-2R alpha | Gp130 |
| CD27/TNFRSF7 |
Human Cytokine Panel
| CCL2/JE/MCP-1 | FGF basic/FGF2/bFGF |
| CCL3/MIP-1 alphaG-CSF | G-CSF |
| CCL4/MIP-1 beta | GM-CSF |
| CCL5/RANTES | IFN-gamma |
| CD27/TNFRSF7 | IL-1 alpha/IL-1F1 |
| CXCL5/ENA-78 | IL-1 beta/IL-1F2 |
| IL-1ra/IL-1F3 | IL-4 |
| IL-2 | IL-5 |
| IL-8/CXCL8 | IL-6 |
| IL-10 | IL-17/IL-17A |
| TNF-alpha | Thrombopoietin/Tpo |
| VEGF |
Human MMP Panel
| EMMPRIN/CD147 | MMP-8 |
| MMP-1 | MMP-9 |
| MMP-2 | MMP-10 |
| MMP-3 | MMP-12 |
| MMP-7 | MMP-13 |
Human Growth Factor Panel
| IL-9 | EGF |
| CCL3/MIP-1 alpha | FGF basic/FGF2/bFGF |
| CCL19/MIP-3 beta | Flt-3 Ligand/FLT3L |
| CD40 Ligand/TNFSF5 | G-CSF |
| CXCL2/GRO beta/MIP-2/CINC-3 | Granzyme B |
| IFN-beta | IL-3 |
| IL-8/CXCL8 | IL-17E/IL-25 |
| IL-33 | PD-L1/B7-H |
| PDGF-AA | PDGF-AB/BB |
| TGF-alpha | TRAIL/TNFSF10 |
| VEGF |
Human TGF-beta Panel
| TGF-beta 2 | TGF-beta 3 |
Human TIMP Panel
| TIMP-1 | TIMP-2 |
| TIMP-4 |
Human Th1/Th2 Performance Panel
| IL-9 | GM-CSF |
| IFN-gamma | IL-1 beta/IL-1F2 |
| IL-2 | IL-4 |
| IL-5 | IL-6 |
| IL-10 | IL-12 p70 |
| IL-13 | Lymphotoxin-alpha/TNF-beta |
| TNF-alpha |
Human Th9/Th17/Th22 Performance Panel
| IL-9 | IL-2 |
| CCL20/MIP-3 alpha | CD40 Ligand/TNFSF5 |
| GM-CSF | IFN-gamma |
| IL-1 beta/IL-1F2 | IL-4 |
| IL-5 | IL-6 |
| IL-10 | IL-12 p70 |
| IL-17/IL-17A | IL-17E/IL-25 |
| IL-33 | TNF-alpha |
| IL-13 | IL-15 |
Biomarker Panels by Indication
Select each panel to see the analytes included
Human Tumor Biomarker Panel
| CA15-3/MUC-1 | Chromogranin A |
| CA19-9 | Glypican 1 |
| CD40 Ligand/TNFSF5 | FGF basic/FGF2/bFGF |
| CEACAM-5/CD66e | Fas/TNFRSF6/CD95 |
| CYFRA21-1 | Fas Ligand/TNFSF6 |
| Chorionic Gonadotropin beta Chain (HCG beta) | Enolase 2/Neuron-specific Enolase |
| HE4/WFDC2 | HGF |
| IL-6 | IL-8/CXCL8 |
| Kallikrein 3/PSA | Leptin/OB |
| Osteopontin/OPN | Prolactin |
| SCF/c-kit Ligand | TGF-alpha |
| Thyroglobulin | TNF-alpha |
| VEGF | alpha-Fetoprotein/AFP |
Immuno-Oncology Panel
| PD-L2/B7-DC | CTLA-4 |
| TIM-3 | CXCL5/ENA-78 |
| CCL17/TARC | HVEM/TNFRSF14 |
| CD25/IL-2R alpha | IFN-gamma |
| CD27/TNFRSF7 | LAG-3 |
| CD28 | OX40 Ligand/TNFSF4 |
| CD40/TNFRSF5 | PD-L1/B7-H1 |
Human Circulating Cancer Biomarker Panel
| Antithrombin III |
| Complement Factor H (CFH) |
| Vitamin D binding protein |
| Extracellular matrix Protein 1 (ECM1) |
Human Cancer Metastasis Panel
| DKK1 | Osteoprotegerin (OPG) |
| GDF15 | Periostin |
| Neuron-specific Enolase (NSE) | Osteonectin/SPARC |
| TWEAK | TRAP5 |
| YKL40/CHI3L1 |
Human Angiogenesis/Growth Factor Panel
| Angiopoietin-2 | EGF |
| BMP-9 | Endoglin |
| Endothelin-1 | FGF-1/FGF-acidic |
| FGF-2/FGF-basic | Follistatin (FST) |
| G-CSF | HB-EGF |
| HGF | IL-8/CXCL8 |
| Leptin | Placental Growth Factor (PGF) |
| VEGF-C | VEGF-A |
| VEGF-D |
Human Exosome Characterization Panel
| Argonaute-2 (Ago2)* | Calreticulin (CALR) |
| CD9 | CD63 |
| CD81 | Flotillin-1 (FLOT-1) |
| GAPDH | Syntenin-1 (Syn-1) |
| TSG10 |
Human Metabolic Panel
| C-Peptide | CCL2/JE/MCP-1 |
| CCL2/JE/MCP-1 | Ghrelin |
| Glucagon | IFN-gamma |
| IL-6 | Insulin |
| Leptin/OB | Pancreatic Polypeptide/PP |
| Peptide YY | TNF-alpha |
Human Obesity Panel
| Adiponectin/Acrp30 | C-Reactive Protein/CRP |
| CCL2/JE/MCP-1 | Complement Factor D/Adipsin |
| IL-6 | IL-10 |
| Leptin/OB | Resistin |
| Serpin E1/PAI-1 | TNF-alpha |
Human IGF Binding Protein Panel
| IGFBP1 | IGFBP5 |
| IGFBP2 | IGFBP6 |
| IGFBP3 | IGFBP7 |
| IGFBP4 |
Human Pituitary Panel
| ACTH | CNTF |
| FSH | GH |
| TSH | LH |
|
Agouti-Related Protein (AgRP) |
Bio-Plex Pro™ Human Inflammation Panel
| APRIL / TNFSF13 | BAFF / TNFSF13B |
| sCD30 / TNFRSF8 | Chitinase-3-like 1 |
| sCD163 | Chitinase-3-like 1 |
| gp130 / sIL-6Rβ | IFN-α2 |
| IFN-β | IFN-γ |
| IL-2 | sIL-6Rα |
| IL-8 | IL-10 |
| IL-11 | IL-12 (p40) |
| IL-12 (p70) | IL-19 |
| IL-20 | IL-22 |
| IL-26 | IL-27 (p28) |
| IL-28A / IFN-λ2 | IL-29/IFN-λ1 |
| IL-32 | IL-34 |
| IL-35 | LIGHT / TNFSF14 |
| MMP-1 | MMP-2 |
| MMP-3 | Osteocalcin |
| Osteopontin | Pentraxin-3 |
| sTNF-R1 | sTNF-R2 |
| TSLP | TWEAK / TNFSF12 |
Human Treg Cytokine Panel
| IL-2 | IL-10 |
| IL-12 (p40) | IL-12 (p70) |
| IL-19 | IL-20 |
| IL-22 | IL-26 |
| IL-27 (p28) | IL-28A / IFN-λ2 |
| IL-29 / IFN-λ1 | IL-35 |
Human Kidney Biomarker Panel
| Clusterin | CXCL10/IP-10/CRG-2 |
| Cystatin C | Lipocalin-2/NGAL |
| Osteopontin/OPN | TFF3 |
Human Kidney Injury Panel 1
| Calbindin | Collagen IV |
| GSTα | IP-10/CXCL10 |
| KIM-1 | Renin |
| TFF-3 | TIMP-1 |
Human Kidney Injury Panel 2
| α-1-Microglobulin | Albumin |
| Clusterin | Cystatin C |
| EGF | NGAL/Lipocalin-2 |
| Osteopontin (OPN) |
Human Kidney Injury Panel 4
| EGF | FABP1 |
| IP-10/CXCL10 | KIM-1 |
| Osteopontin (OPN) | PTH |
| Renin |
Human Alzheimer Panel (Amyloid Beta and Tau)
| Amyloid beta 1-40 | Amyloid beta 1-42 |
| pTau (Thr181) | Tau (total) |
Human Neurodegenerative Autoantibody IgG Panel
| α-synuclein | Aβ42 |
| AChR | AGNA (SOX1) |
| Ago2 (Su) | AMPA-R |
| Amphiphysin | ANNA2 (Ri)/NOVA1 |
| AQP4 | C1q |
| CRMP5 | CRYAB |
| DPPX | DRD2 |
| ELAVL4 (HuD) | GFAP |
| MOG | NF-L |
| NMDAR1 | NRXN3 |
| PNMA1 (Ma1) | PCA1 (Yo)/CDR2 |
| MBP | mGluR1 |
| TTau |
Human Neurological Disorders Panel
| Angiotensinogen (AGT) | Contactin-1 |
| Fetuin A | Kallikrein-6 |
| Osteopontin (OPN) | Soluble Superoxide |
| Dismutase 1 (sSOD1) | Dismutase 2 (sSOD2) |
ELLA® Simple Plex Assays
Biomarker Panels by Indication
Select each panel to see the analytes included
Mouse
| Adiponectin | Cystatin C | IL-1 beta | MMP-9 | Thrombospondin-4 |
| Angiopoietin-2 | Dkk-1 | IL-2 | MMP-12 | TIM-1/KIM-1 |
| BAFF/BLyS | DPPIV/CD26 | IL-3 | Nephrin | TIMP-1 |
| CRP | EGF | IL-4 | beta-NGF | TIMP-4 |
| C1qR1 | EGF R | IL-5 | Oncostatin M | TNF-alpha |
| CCL2/MCP-1/JE | EMMPRIN | IL-6 | Osteopontin | TNF RI |
| CCL3/MIP-1 alpha | Endoglin | IL-6 R alpha | Osteoprotegerin | TNF RII |
| CCL4/MIP-1 beta | FABP4/A-FABP | IL-7 | Pancreatic Polypeptide | TRANCE/RANK L |
| CCL5/RANTES | Fas Ligand | IL-9 | PDGF-AA | TWEAK |
| CCL7/MARC | FGF basic | IL-10 | PDGF-AB | uPAR |
| CCL8/MCP-2 | FGF-21 | IL-12 p70 | PDGF-BB | VEGF |
| CCL11/Eotaxin | G-CSF | IL-13 | Periostin/OSF-2 | VEGF R2 |
| CCL12/MCP-5 | Galectin-3 | IL-16 | PlGF-2 | |
| CCL19/MIP-3 beta | GDF-15 | IL-17A | Podocalyxin | |
| CCL20/MIP-3 alpha | Glucagon | IL-17E/IL-25 | Prolactin | |
| CCL21/6Ckine | GM-CSF | IL-23 p19 | PCSK9 | |
| CCL22/MDC | Granzyme B | IL-27 | RAGE | |
| Chitinase 3-like 1/ YKL-40 | Haptoglobin | IL-33 | Renin | |
| Factor D/Adipsin | HGF | LDL R | Resistin | |
| CXCL1/KC | ICAM-1 | Lipocalin-2/NGAL | S100A8 | |
| CXCL2/MIP-2 | IFN-gamma | LIX | S100A9 | |
| CXCL10/IP-10 | IGF-I | M-CSF | P-Selectin | |
| CXCL12/SDF-1 alpha | IGFBP-1 | MMP-2 | Serpin E1/PAI-1 | |
| CXCL13/BLC/BCA-1 | IGFBP-3 | MMP-3 | SOST | |
| CXCL16 | IL-1 alpha | MMP-8 | SP-D |
Rat
| EGF | Eotaxin/CCL11 | Fractalkine | G-CSF | GM-GSF |
| GRO/KC | IFN-ϒ | IL-1α | IL-1β | IL-2 |
| IL-4 | IL-5 | IL-6 | IL-10 | IL-12 (p70) |
| IL-13 | IL17A | IL-18 | IP-10 | Leptin |
| LIX | MCP-1 | MIP-1α | MIP-2 | RANTES |
| TNF-α | VEGF |
Veterinary / in Vivo Biomarker Services
SBH Sciences offers a wide range of Biomarker evaluations for Veterinary / in Vivo studies. We deliver precise and reliable services for both preclinical studies, and ultimately for clinical end points and studies.
SBH Sciences provides full Biomarker Testing including:
* Luminex Capability
* WES/ PEGGY Western Blot Capability
* Development of custom ELISA kits
* Custom production of Protiens
SBH Sciences provides Biomarker evaluations for: Rodent (mouse/ rat), Canine, Porcine and Equine Veterinary and in Vivo studies. See our Detailed in Vivo Biomarker Services listings below.
Accelerate your drug discovery & development With Us
Find out more about SBH Sciences (PDF file).
In Vivo Biomarker Services - Mouse
SBH Sciences offers Biomarker evaluations for the Veterinary / in Vivo studies of Mice. We deliver precise and reliable services for both preclinical studies, and ultimately for clinical end points and studies. SBH Sciences provides full biomarker services including: Luminex Capability, WES/ PEGGY Western Blot Capability, Development of custom ELISA kits, as well as the Custom production of Proteins.
We currently provide Biomarker testing for the following Mouse Analytes:
| Adiponectin | Cystatin C | IL-1 beta | MMP-9 | Thrombospondin-4 |
| Angiopoietin-2 | Dkk-1 | IL-2 | MMP-12 | TIM-1/KIM-1 |
| BAFF/BLyS | DPPIV/CD26 | IL-3 | Nephrin | TIMP-1 |
| CRP | EGF | IL-4 | beta-NGF | TIMP-4 |
| C1qR1 | EGF R | IL-5 | Oncostatin M | TNF-alpha |
| CCL2/MCP-1/JE | EMMPRIN | IL-6 | Osteopontin | TNF RI |
| CCL3/MIP-1 alpha | Endoglin | IL-6 R alpha | Osteoprotegerin | TNF RII |
| CCL4/MIP-1 beta | FABP4/A-FABP | IL-7 | Pancreatic Polypeptide | TRANCE/RANK L |
| CCL5/RANTES | Fas Ligand | IL-9 | PDGF-AA | TWEAK |
| CCL7/MARC | FGF basic | IL-10 | PDGF-AB | uPAR |
| CCL8/MCP-2 | FGF-21 | IL-12 p70 | PDGF-BB | VEGF |
| CCL11/Eotaxin | G-CSF | IL-13 | Periostin/OSF-2 | VEGF R2 |
| CCL12/MCP-5 | Galectin-3 | IL-16 | PlGF-2 | |
| CCL19/MIP-3 beta | GDF-15 | IL-17A | Podocalyxin | |
| CCL20/MIP-3 alpha | Glucagon | IL-17E/IL-25 | Prolactin | |
| CCL21/6Ckine | GM-CSF | IL-23 p19 | PCSK9 | |
| CCL22/MDC | Granzyme B | IL-27 | RAGE | |
| Chitinase 3-like 1/ YKL-40 | Haptoglobin | IL-33 | Renin | |
| Factor D/Adipsin | HGF | LDL R | Resistin | |
| CXCL1/KC | ICAM-1 | Lipocalin-2/NGAL | S100A8 | |
| CXCL2/MIP-2 | IFN-gamma | LIX | S100A9 | |
| CXCL10/IP-10 | IGF-I | M-CSF | P-Selectin | |
| CXCL12/SDF-1 alpha | IGFBP-1 | MMP-2 | Serpin E1/PAI-1 | |
| CXCL13/BLC/BCA-1 | IGFBP-3 | MMP-3 | SOST | |
| CXCL16 | IL-1 alpha | MMP-8 | SP-D |
In Vivo Biomarker Services - Rat
SBH Sciences offers Biomarker evaluations for the Veterinary / in Vivo studies of Rats. We deliver precise and reliable services for both preclinical studies, and ultimately for clinical end points and studies. SBH Sciences provides full biomarker services including: Luminex Capability, WES/ PEGGY Western Blot Capability, Development of custom ELISA kits, as well as the Custom production of Proteins.
We currently provide Biomarker testing for the following Rat Analytes:
| EGF | IL-1α | IL-12 (p70) | MCP-1 |
| Eotaxin/CCL11 | IL-1β | IL-13 | MIP-1α |
| Fractalkine | IL-2 | IL-17A | MIP-2 |
| G-CSF | IL-4 | IL-18 | RANTES |
| GM-CSF | IL-5 | IP-10 | TNF-α |
| GRO/KC | IL-6 | Leptin | VEGF |
| IFN-γ | IL-10 | LIX |
In Vivo Biomarker Services - Canine
SBH Sciences offers Biomarker evaluations for the Veterinary / in Vivo studies of Canines. We deliver precise and reliable services for both preclinical studies, and ultimately for clinical end points and studies. SBH Sciences provides full biomarker services including: Luminex Capability, WES/ PEGGY Western Blot Capability, Development of custom ELISA kits, as well as the Custom production of Proteins.
We currently provide Biomarker testing for the following Canine Analytes:
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In Vivo Biomarker Services - Pig
SBH Sciences offers Biomarker evaluations for the Veterinary / in Vivo studies of Pigs. We deliver precise and reliable services for both preclinical studies, and ultimately for clinical end points and studies. SBH Sciences provides full biomarker services including: Luminex Capability, WES/ PEGGY Western Blot Capability, Development of custom ELISA kits, as well as the Custom production of Proteins.
We currently provide Biomarker testing for the following Pig Analytes:
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In Vivo Biomarker Services - Equine
SBH Sciences offers Biomarker evaluations for the Veterinary / in Vivo studies of Equines. We deliver precise and reliable services for both preclinical studies, and ultimately for clinical end points and studies. SBH Sciences provides full biomarker services including: Luminex Capability, WES/ PEGGY Western Blot Capability, Development of custom ELISA kits, as well as the Custom production of Proteins.
We currently provide Biomarker testing for the following Equine Analytes:
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Master List of Biomarkers
| Test Name | Method |
| 4-1BB | ELISA |
| Adiponectin | ELISA |
| Asymmetric dimethyl arginine (serum) | ELISA |
| BD-1 | ELISA |
| Beta-2-microglobulin (urine) | ELISA |
| BMP-2 | ELISA |
| BMP-7 | ELISA |
| C-Peptide | ELISA |
| C Reactive Protein | ELISA |
| Caspase 3/7 | Activity Assay |
| CD14 (serum) | ELISA |
| CD40 Ligand (Soluble) | Luminex |
| CD47 (serum) | ELISA |
| CD163 (serum) | ELISA |
| chemokine (C-X-C motif) ligand 1 (CXCL1) | Luminex |
| Cleaved cytokeratin 18 (serum) | ELISA |
| Clusterin (urine) | ELISA |
| Cystatin C (urine) | ELISA |
| Cytokeratin 18 (serum) | ELISA |
| Cytomegalovirus IgG (serum) | ELISA |
| EGF | ELISA or Luminex |
| Eotaxin | Luminex |
| Eotaxin-3/CCL26 | Luminex |
| FGF-basic | ELISA or Luminex |
| Fms-related tyrosine kinase 3 ligand | Luminex |
| Fractalkine | Luminex |
| Galectin 1 | ELISA |
| Galectin 3 | ELISA |
| G-CSF | ELISA or Luminex |
| GDF-15 / MIC-1 | ELISA |
| Glucagon | ELISA |
| GM-CSF | ELISA or Luminex |
| Granzyme B | ELISA |
| High mobility group box 1 protein | ELISA |
| ICAM-1 | Luminex |
| IGF-BP1 | ELISA |
| Insulin | ELISA |
| Interferon alpha 2 | Luminex |
| Interferon gamma | Luminex |
| Interferon gamma-induced protein 10 | Luminex |
| Interleukin 1 alpha | Luminex |
| Interleukin 1 recepter antagonist | Luminex |
| Interleukin 1 beta | Luminex or Simple Plex |
| Interleukin 2 | Luminex |
| Interleukin 2 receptor antagnoist | Luminex |
| Interleukin 3 | Luminex |
| Interleukin 4 | Luminex |
| Interleukin 5 | Luminex |
| Interleukin 6 | ELISA or Luminex or Simple Plex |
| Interleukin 7 | Luminex |
| Interleukin 8 | ELISA or Luminex or Simple Plex |
| Interleukin 9 | Luminex |
| Interleukin 10 | ELISA or Luminex or Simple Plex |
| Interleukin 12p40 | Luminex |
| Interleukin 12p70 | Luminex |
| Interleukin 13 | Luminex |
| Interleukin 15 | Luminex |
| Interlukin 16 | ELISA |
| Interleukin 17A | Luminex |
| Interluekin 18 | ELISA |
| Kidney Injury Molecule 1 (urine) | ELISA |
| Leptin | ELISA |
| Macrophage inflammatory protein 1 beta | ELISA or Luminex or Simple Plex |
| Measles Virus IgG (serum) | ELISA |
| Monocyte Chemoattractant Protein 1 alpha (serum) | ELISA or Luminex or Simple Plex |
| Monocyte Chemoattractant Protein 3 | Luminex |
| Monocyte Chemoattractant Protein 4 | Luminex |
| Macrophage-derived chemokine | Luminex |
| Neutrophil gelatinase-associated lipocalin (plasma) | ELISA |
| Neutrophil gelatinase-associated lipocalin (urine) | ELISA |
| Perforin | ELISA |
| PIGF | Luminex |
| Platelet-derived growth factor AA | Luminex |
| Platelet-derived growth factor AB/BB | Luminex |
| Protein Carbonyl | ELISA |
| RANTES (serum) | ELISA or Luminex |
| Resistin | ELISA |
| SAA | ELISA |
| TARC/CCL17 | Luminex |
| Thrombopoietin | ELISA |
| Tie-2 | Luminex |
| Transforming growth factor alpha | Luminex |
| Transforming growth factor beta 1 (serum) | ELISA |
| Tumor Necrosis Factor alpha | ELISA or Luminex or Simple Plex |
| Tumor Necrosis Factor beta | Luminex |
| VCAM-1 | Luminex |
| VEGF-A | ELISA or Luminex |
| VEGF-C | ELISA |
| VEGF-D | Luminex |
| VEGFR1 | ELISA |