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Description :
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Transforming Growth Factor-beta2 (TGF-beta2)
is a member of a superfamily of homologous, disulfide-linked, homodimeric
proteins that regulate the proliferation and differentiation of
normal and transformed cells. Human TGF-beta2 is a 25.0 kDa protein
with each subunit containing 112 amino acid residues.
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Catalog #:
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002-TGF2
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Source :
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HEK293 Cells
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Formulation :
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Lyophilized from Sodium Citrate, pH 3.5 buffer.
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Stability :
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The lyophilized protein is stable for a few
weeks at room temperature, but best stored at -200C.
Reconstituted TGF-beta2 should be stored in working aliquots at
-200C.
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Purity :
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Greater than 98% by SDS-PAGE. Endotoxin level
is less than 0.1 ng per μg (1EU/μg).
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Reconstitution :
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We recommend a quick spin followed by
reconstitution in water to a concentration of 50 ug/ml. This
solution can then be stored at 40C
for 1 month. It is recommended that further dilutions be made
in PBS containing 2mg/ml albumin and stored at -800C.
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Biological Activity :
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Determined by its ability to inhibit the mouse
IL-4-dependent proliferation of mouse HT-2 cells. The ED50 was found
to be <0.2ng/ml, corresponding to a specific activity of >5 x 106
units/mg.
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AA Sequence :
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ALDAAYCFRN VQDNCCLRPL YIDFKRDLGW KWIHEPKGYN
ANFCAGACPY LWSSDTQHSR VLSLYNTINP EASASPCCVS QDLEPLTILY YIGKTPKIEQ
LSNMIVKSCK CS
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PubMed Link :
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TGFbeta2
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Usage:
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For research Purposes Only - Not for use in
diagnostic or therapeutic procedures.
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Country of Origin :
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USA
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