---
title: Human CD22 Recombinant Protein
description: Activin-A is a TGF-beta family member involved in the regulation of cellular proliferation and differentiation, and promotion of neuronal survival.
image: https://sbhsciences.com/hubfs/Screenshot%202026-01-20%20at%202.01.44%20PM.png
---

<https://sbhsciences.com/blog/human-cd22-recombinant-protein#body>

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![Human CD22 Recombinant Protein](https://sbhsciences.com/hubfs/Screenshot%202026-01-20%20at%202.01.44%20PM.png)

# *[cancer](https://sbhsciences.com/blog/tag/cancer) | [immune/inflammation](https://sbhsciences.com/blog/tag/immune-inflammation)* Human CD22 Recombinant Protein

Catalog #001-HCD22

 

 Description

 

CD22 is a 135 kDa B-cell restricted sialoglycoprotein that binds to oligosaccharides containing 2-6-linked sialic acid residues. It is present in the cytoplasm of nearly all B-lineage cells and is also expressed on the surface of B-cells during advanced stages of differentiation. Although the exact physiological function of CD22 is unclear, it appears to play a role in B-cell activation and to act as an adhesion molecule. The potential therapeutic use of CD22 and anti-CD22 may be useful in diagnostic and/or treatment of leukemia, lymphoma, non-Hodgkin’s lymphoma and certain autoimmune conditions. Recombinant human CD22 is a soluble 75.0 kDa (666 amino acid residues) protein which corresponds to the extracellular domain of CD22.

 

###### Product Specific Information

 

Reconstitution: We recommend a quick spin followed by reconstitution in water to a concentration of 0.1-1.0 mg/ml.

Storage: Store at -20°C for long-term stability.

| PROPERTIES |  |
| --- | --- |
| Species | Human |
| Expression System | Chinese Hamster Ovary (CHO) Cells |
| Molecular Weight | 75 kDa |
| Full Length | 666 amino acids |
| Purity | ≥98% by SDS-PAGE and HPLC Analyses |
| Form | Lyophilized |
| Endotoxin | \<1 EU/µg |
| Activity | Determined by it's ability to induce cytotoxicity in Raji cells. The ED50 for this effect is 10 - 15 ug/ml |
| Storage | -20°C |

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